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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e1fb47fd745b9739f4076fb45d5d6a94c38c657a7dbafb6a8e7113a5b7be07' 
  AND token = 'OV2sI3vSS0g5OMEI7Z2VNV3+dYyCUdjZXNi3yR70u7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}