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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521e5807361ce5f9eb5a212f24ee85f60af0aad60e3974d37b866f1645ab5d18' 
  AND token = 'cnzjCFDhHdcUdk6OnCQaq6FdKVgnchkJvI2nBeMEkcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}