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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a9b804cbcc622cc543a0557a302b1b5502b4719aede7b34bdacbf278ad1ba8' 
  AND token = 'UusOiMn/mXYSS4lFkVjB//EfRy+RQI3evlAnMyC3phU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}