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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948b066348735226f61e2dd40752f007cf58b9fa416529b616465a331e69b751' 
  AND token = 'rH0fRgp6sfLW1Mb/vmKKicKD/bDnrTIhyN6oaFyPBfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}