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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e2ba48bffaa0e31b459f0f6e4596e7011c4e5c91816721c018f23dc2b12da7' 
  AND token = '4O+oEOS1sdfGe2TiCDIa70DQtO4biBsoF/hnts4m9+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}