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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a71d1b31d94d7c945c28e9d60610b1454d8c1cfd5bb028b2c675df8b49df729' 
  AND token = 'GL76nRmzAeuVVjlXC410Y0bmoYbMH+9TuanxJVUe2mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}