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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c53475ed031c9ca9a6d532ada862c91274623f1bbff1eea5150a11d4932287' 
  AND token = '++V24m3WyMQB9n+NqGBDeNismCvl/gh9gXdb/o4C7rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}