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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cde8953ce3d0699fba803e17a8a7cc7f774fb1082a34315014c6d279168d3f5' 
  AND token = '4pALitf0ayYNB1hh5LsE9l54nZ3F/x7CP5+E60RFlRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}