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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a33a725a995c60c88a9b23c06df24d11e509cfdad40447a48d42872fcc2931' 
  AND token = 'UuQqiLwM370hB51K7Hn4LZ1d9VDj3blWGm9vp1myF9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}