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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9722864cabad10bd6c6d929046efc46b167b1e9e53207b14d0d6b3cbd2273b71' 
  AND token = 'ppqdPZj/0QeQLVg/XNp7hlfNU5woIgag/dpzw/3oiP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}