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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1beaaf085342b91f4efae738b3ad044a6c25374ad0a83edea56a62993a18c4c6' 
  AND token = 'K07fbt+dE6GZb80hsUvDwT8rxiHViLswYQ5TEHziPUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}