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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005146799095438606da3aa995827a8d7bbf9d92ad061a7885528e5130bb8e1e' 
  AND token = 'Wv4b7seRjY0MC3yq/f0K/y1LLIx1argVvZKNQvIDyBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}