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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1c2124a43b25ae7dce74dfeb89907102091e94a8bea4d9094e6e042c84245d' 
  AND token = 'ZcLzEIEfoyPD0aHTKiZhlaYk/qE94AW0G2dYa+PIEGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}