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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eabc32e8f16da3ffe952c938c94b0261e75dd21fbe64b326ea851c72e29c850' 
  AND token = 'yXe5gWNsaMaD8qmSSdVUy29P0YY03MeXyWAf4jfovOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}