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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855f68190c0c2227bf6d5513a3e344638e3460628fab94bdeaa3aa5d3a9d7713' 
  AND token = '8tqXbd+rMMl2+RaDUNaXzHf+OK+9v8c54oJ3qjJi5Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}