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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468a23c0d0e0e52be209cb7dcc72de30cdb271761dfa571c219e7c170d91fa05' 
  AND token = '3PRHgYWo4rjBEii2wlqUgwVPfm/o8fzhZ0TeQRDduwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}