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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6511f5db6b01b595e76658f5d2d28b7a59f518b82b4146ef00e94289f1d26cd' 
  AND token = '653cmve/YDEIaURuk/c+xrm+KEykWOmSYwsJ/y4ut3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}