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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8555b71803efa19dae2468719173e4492769f8f938b1ddcc23f8b6dc05c8e9f' 
  AND token = 'cS3H8M+jgrMwyE3FD3U7HJ0kA+uAKNTWRNTEzfFp0GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}