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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6cdbb2bcbffb4d65e453a442b54c14e1439ba1add1e1d3a1e7911d3fe45472' 
  AND token = 'kRh3Gnp8y9/PI6hPtqEBkEIWJrqSruRIqm8MuVmLzvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}