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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1e7769b17974d0f902cb75f6622a8d506bc6a1f312a62f8f5ac2bfdb84df58' 
  AND token = 'DUdmFDykJ9oph0sUC0oU/b+wc6bJvHbRjheRWVTypW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}