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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a33a8d85bdf9340dede7aeccf167015364c7ef3cebfa3fb0049bcc9867b6d4da' 
  AND token = 'ZEgE58721AQ6fBmcYcQwC3KjdLENE/JHxxl/rVaZYi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}