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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '088c80592815756be4ba8b0c6988f0fcdbe8d8c17086971624d0b48e492a4f8d' 
  AND token = 'OfooD8ULu6+TOg2mRC+xKsxFYom8NHLji+mS7s6yJHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}