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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd827701be0ef20baa8df123d05912e5944de1276a0e44b1e58c7563eff28f72' 
  AND token = 'cJLi9Urt+RGRPTi4ONR8mtBGPVyzz1jzcsD46z0/CBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}