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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf5b1b19da5045fb204916502358b0c292bec14c009781217fef2e5eb3f3622' 
  AND token = 'hGlWTI0byIkKSACE1S3ueqKIh86aQLd4KpL0kxBft30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}