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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1d667159b4e64426a6e4a2cd90717446d6aeb859cdac9dc1a227820ddb4ec6' 
  AND token = 'z024W4WuhW9Ai8cFEnzG/OOm/0Tq8kOZFm36IxZlgY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}