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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2d198b63dc0171e3d93ded0ad6d0dc77f2a37e9aef6fea514096e4c393d310' 
  AND token = 'LPtlFe7Vv8HFWG+WaA7oezhwDf9AYPDp6W99LXS0DRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}