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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6502be9a428581322538bd64feca5b8dfc3f007e9a852412e83b8060ce3dbe8' 
  AND token = '1+4/SaUCRU9i9NkjY7FwK2IdxZ4fL81IwTOAr6N7NdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}