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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a07202e05910a0190aede878aa18fb4defd4e30f6a10251f51c678ce8f00ceb' 
  AND token = 'cMp0IIBKK4T6o+qCxcCQR/2Rkg3XUY0Wjk/UUxewVUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}