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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6d25b99467ce0b1472873e1c0adcba8d98793510b2874d6b0dea49cd23d331' 
  AND token = 'xH4Z3I2UdBtGa/EJ7KHGRcVHgQQQuMg983YI63sd89c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}