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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067b48876eea11c61dd553eae46e6ea93244ffd6bdc1ed8b962731de29d827bc' 
  AND token = 'AqVzPDk3djpv+rrkl0f6eAswmFJB90aIwE9Qyvo+V9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}