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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6981387e599e94dd1fb1c7f027f7d4f519274be77f2a484e2059bf5ec2be7d' 
  AND token = 'Gjc18JSnsKB6634DY8hgHrxjcpcqUtQAzePiKQogqEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}