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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6d12606b8ede80939dfae35ca518d009b19a5c4ef34541cbcb23b48fe72310' 
  AND token = '51LM4oXEaU/oMf1j3A3MfL8pBAtJnDVZ4Xw5uMHwOCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}