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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f1003e3dcc6d9613ba79f6d83549dbed68c0288afaf553410b1505f2772ec0' 
  AND token = 'x6WFfnDYaVvrkgSPHs7L3YNDM+QqiCq2TYXw4j+pkdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}