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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4889ea4ca896a48d5eebbc6e5cdb0dc633b346c81b4484baac4cc91fc60fb066' 
  AND token = 'm59CMweYuK2/U47T47993ivUcC7A50aWxKwzb3kpidk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}