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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325ae8c32b7a93b3f4efca9f0c8143482ee7d298dc6ee123cee5066834f07e21' 
  AND token = 'VFv0Y+pLEZqk6DmCZwdgmDLF0lVIdy2Yl2PvU44oQyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}