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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e876c19a0b24347921a17211fe54e3b250bfc2cd1cb77d346211b34c215d21' 
  AND token = '8Iz4+3LS3QVaNL6MMhzaY5SYvnvAaDCq8sLgcdH4Q8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}