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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad972a2a31f6ae05263f8605c9f9e121c9e6168d973b50166884cd20854457f' 
  AND token = 'hSe+FeWbev0x2djxIWlGs40CPqbz5+k4zP8TnUiB2DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}