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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43916d9a4487d3248157b18b7087c91f68c1fec4a1a705bcea70513de18b0b0a' 
  AND token = '/mG8EnK7n7zrU4WRpif0wZtJjtJWI80s/8QfdQvH7vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}