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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec791f0d661c9b54e445640df17d17e53901e0234c40ae5ceb93af349925a6b3' 
  AND token = 'vdMl5mST1oc89mCdQsntexLnF/uje08Z1H5sMKbxWNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}