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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f173ee99f3dd4c35f4d815bc996337f6eb7f5ffc30593bd72189e2403abb11' 
  AND token = 'zEQMRf3bQTnUm+Or2BQ7vbDiU4QcuqdEmvn1hpl1K9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}