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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cefe045fb6e0a6017036042e332975ad9e3fc5a27106c2cd46709a13a8ad787' 
  AND token = 'XBFm+IGg3o6YmyTTGxr34MOMIIE18pHMMxzlROtFPd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}