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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c3275a1118a4c163719c79eae4df728843492f1ce7fbbd350e7322696a1385' 
  AND token = 'gPxn+7eWO8doOHzvEuFsDLHEq4DYNyNux9iyWu0sF2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}