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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af16616a90d5b05e8d99c45b33568c0103a5ad1b6452c94ceb3df3a076ec606f' 
  AND token = 'DwpIcdyMFZbmRAArBJ6Ra1b0ogczEwnNW6MVbCcszoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}