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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5c0091ad127aa7947a82807b3cf66f228e36f99ada94aee18a2793ffbeed72' 
  AND token = 'u5BcFqa66+aXyzaTYFq46/uBVfNNvb4KVMKyCiJr9lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}