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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583e2123d24bba6c6890a195fc23de0e47dcffb5e8286417e4816c43e58818fd' 
  AND token = 'oiPq4cPiRWdTHIwXIFHDODUcWO2eVdh/NYuQRNzGzck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}