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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422298c1da8ab7e704e4636e79ad12eaea63fa85a07d542ebaaf8dc84ad91b6a' 
  AND token = 'sZLxEWLXAxi2eki6G0epnNa2Wj1D3EoWJiam1CtOMXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}