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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a23b51eb14b351bf21f1a704a4cd760ee17c7230b7f208bf963827f9beccda2' 
  AND token = 'uc/vmIe+c4YR1r61p0DNEyXe0TX+9oQ+b12w/wIcyl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}