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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13d64c39d7289c087c20123e465ad2da80d36c7c4ec4e432fb85eacf3b0c6f3' 
  AND token = '9T2lFfHEzQB+SJ3WyqZ1E2mPS6KnR8KEsBbZiCbgS4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}