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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afda356870474e46326fb609f35dccaf015a362343e68dbb47df259e47e6940e' 
  AND token = 'tzGb0NodS0NXQCx6g6jq0HAtK5GVFFaBjz7fSxZcyic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}