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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae20f529fd051c13058bf13bae1b8b0bc581dda71ec00166d2fb2e5b71b939f' 
  AND token = '/GXUhRdw00XQRpwtA9aGg/aoUaNTzjIHkZlF7IFKfz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}